Definition: PPD reactivity going from < 5mm to > 15 mm induration in a 2-year period.


CXR to rule out active disease. If positive discuss treatment with MD.

If negative CXR start chemoprophylaxis with Isoniazid (INH) 300 mg PO QD X 6-12 months + Vitamin B6 50 mg PO QD

Monitor CBC, LFTs, INR (if on Coumadin), Q month

Reference: Geriatrics At Your Fingertips, 2005 Edition, p. 74.

MMWR Treatment of Tuberculosis, June 20, 2003, RR(11); 1-77.


Revised 1/06




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